ISSN 2490-3329 (Print)
ISSN 2303-7954 (Online)

Volume 49, Issue 2, Article 11

(Scr Med 2018:49:141-144)

Acute Poisoning with Herbicide Glyphosate

Milidrag Vukotić1, Vesna Paleksić1, Slaviša Narić1

1 Institute for Occupational Health and Sports of Republic of Srpska Banja Luka
2 Faculty of Medicine, University of Banja Luka, Banja Luka, Republic of Srpska, Bosnia and Herzegovina


DOI 10.7251/SCMED1802141V
UDC 615.099:632.954
COBISS.RS-ID 7839512



Glyphosate is the most common used organophosphorus herbicide which most probably inhibits oxidative phosphorylation without leading to the inhibition of esterases. Glyphosate poisoning is mostly the consequence of the synergistic effect of an active substance and surfactant. There is a case of 42-year-old patient who worked on weed spraying with glyphosate, with hand sprinkler. Symptoms of the acute poisoning such as weakness, sweating, nausea, vomiting and stomach ache were visible right after the working period. With biochemical analysis increased activity of the enzymes AST, ALT and y-GT were diagnosed and sanated after aborting an expositions in the period of six months and treatment. In this shown case poisoning was caused during applying herbicides without proper handling with the herbicide and also because of non-compliance of measures in safety and health at work. It is very clear that this is a case of acute poisoning with pesticides which ended with no consequences and was declared as work injury.

Key words: glyphosate, acute poisoning, enzymes, safety and health


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Corresponding author:
Milidrag Vukotić,
e-mail: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Manuscript received: May 21st, 2018
Manuscript accepted: November 19th, 2018